Previous Post I'm really thinking that maybe it has. I'm thinking that maybe people really aren't that interested in aliens coming to earth and giving people super powers and such or some alien artifact giving someone superpowers. I think it's more interesting if they get their powers some other way. What do you think?

I think it depends on the trope the writer wants to address.

If the story's a "straneg visitors" one, where Earth interacts with "the other" for good or ill then the aliens thing is a great and shorthand way of getting that culture clash.

If the story's about something else than that kind of origin works as a one-line explanation if the thrust of the narrative's somewhere else but detracts from suspension of disbelief if its one of many odd elements.

Shared comics universes aside, its usually more effective to have all the weird things precede from one single anomaly (e.g. existence of magic, genetic mutation, one scientific breakthrough etc). If readers have to believe in magics and aliens and mutants and time travel then it gets hard to establish all those things in a credible way.