The Psychic Samurai never had powers, so she would just go on doing what she does already.

Liu Xi Xian would probably go to University (which she might do anyway) and major in chemical sciences - to try and use what she learned from her former powers, and see if she can duplicate it with technology. And possibly make some money trying. Or if magic has been spared she may become less dependent on her inherent powers and use spells she learned instead.

Yuki Shiro would most likely re-establish the detective agency she was trying to establish before the Lair Legion hired her. She might take on Anna as well since the android would be unable to find normal employment otherwise. She never had any super-powers either, but since there's no Lair Legion anymore there's no point in pretending she's a member.

Anna would have a tough time. She's unable to seek normal employment because she's not supposed to exist, and therefore isn't a citizen nor has a social security number, passport, etc. She would have to either return to SPUD or work with Yuki.

Lara Night, being from another universe and the only one left with any power, would have the difficult decision to become a champion of the Parodyverse or return home and visit the Parodyerse only covertly from that point on.